P53 Mediates Interstitial Cystitis Antiproliferative Factor (APF) Induced Growth Inhibition Of Human Urothelial Cells
UroToday.com- Antiproliferative factor (APF) is a sialoglycopeptide elevated in the urine of patients with interstitial cystitis. APF is detectable in the urine of 95% of IC patients as compared to approximately 9% of controls and is also a low molecular weight glycosylated peptide related to the membrane receptor frizzled 8.
