Category: Cystic Fibrosis

Cystic Fibrosis Foundation recently announced an important initiative to double the number of people with cystic fibrosis who participate in clinical trials over the next two years.”To help potential new drugs for CF move swiftly from the research stage into the hands of patients who need them, we need more people with cystic fibrosis to take part in clinical trials,” said Robert J. Beall, Ph.D, president and CEO of the CF Foundation.

Genaera Corporation (Nasdaq: GENR) today announced that, in conjunction with Cystic Fibrosis Foundation Therapeutics, Inc. (CFFT), both parties have agreed for reasons of futility to discontinue the Phase 2 study of LOMUCIN(TM) for the treatment of cystic fibrosis (CF). Genaera also announced that the Phase 2 study of squalamine in prostate cancer, which is an investigator-initiated study funded by the Department of Defense, will also be discontinued.

The state of Florida will begin screening all newborns for cystic fibrosis (CF) starting July 1. Florida joins 36 other states in the country, plus the District of Columbia, to routinely screen for CF at birth. “This is the right thing to do,” said Peter Hodge, a Boca Raton, Fla. father of two daughters with CF. Hodge’s 14-year-old daughter, Olivia, wasn’t diagnosed with the disease until she was a teenager. “We wish our daughter had been diagnosed at birth.

Eurand N.V. (Nasdaq: EURX) today announced results that were presented at the recent European Cystic Fibrosis Society meeting in Antalya, Turkey, held June 13-16. Results from two phase III studies of Zentase(TM) (EUR-1008) showing a statistically and clinically significant improvement in the absorption of fat, protein and nutrients in patients suffering from Exocrine Pancreatic Insufficiency (EPI).

PARI Pharma will present in-vivo study results for their PARI SINUS pulsating drug delivery system as well as lung deposition and pharmacokinetic data of their proprietary inhaled liposomal Ciclosporin A formulation in lung transplant patients at the European Cystic Fibrosis Conference (ECFC) in Belek, Turkey this week.

In a study of children with cystic fibrosis, French researchers found evidence of very early onset defective bone mineralization in the lumbar spine that was not caused by either nutritional status or lung disease. The lumbar spine is that part of the back between the ribs and the pelvis.

Researchers from the Schulich School of Medicine & Dentistry at The University of Western Ontario , working with a group from Edinburgh, have discovered a way to kill the cystic fibrosis superbug, Burkholderia cenocepacia. These investigators, under the leadership of Dr. Miguel Valvano, Department of Microbiology and Immunology, have had their research published in the May issue of the Journal of Bacteriology, and highlighted in Nature Reviews/Microbiology. B.

Researchers at the University of Pennsylvania School of Medicine have discovered that an enzyme produced by lung-infecting bacteria further shuts down a protein that is defective in cystic fibrosis patients. The disruption to this protein that conveys ions from lung cells to airways causes thick mucus to buildup inside the lung. The finding suggests a new therapeutic target for treating lung infections in some cystic fibrosis (CF) patients.

Researchers at the University of Pennsylvania School of Medicine have discovered that an enzyme produced by lung-infecting bacteria further shuts down a protein that is defective in cystic fibrosis patients. The disruption to this protein that conveys ions from lung cells to airways causes thick mucus to buildup inside the lung. The finding suggests a new therapeutic target for treating lung infections in some cystic fibrosis (CF) patients.

The Cystic Fibrosis Foundation announced today the kick-off of GREAT STRIDES, a national walk benefiting critical cystic fibrosis research, education and care programs. GREAT STRIDES, now in its 19th year, is the largest CF fund-raiser and seeks to raise $36 million nationwide in 2007. Tens of thousands of walkers are expected to turn out at 550 walk sites nationwide from March to June. Some walks will coincide with National Cystic Fibrosis Awareness Month in May.